anti-HMBS antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG58846
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HMBS |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HMBS |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-361 of Human HMBS (NP_000181.2). |
| 偶联标记 | Un-conjugated |
| 別名 | HMBS; Hydroxymethylbilane synthase; Porphobilinogen deaminase; PORC; PBGD; EC 2.5.1.61; Pre-uroporphyrinogen synthase; PBG-D; UPS |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HeLa | ||||
| 实际分子量 | 45 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HMBS |
| 全名 | hydroxymethylbilane synthase |
| 背景介绍 | This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| 生物功能 | Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 39 kDa |
检测图片 (1)
ARG58846 anti-HMBS antibody WB image
Western blot: 25 µg of HeLa cell lysate stained with ARG58846 anti-HMBS antibody at 1:1000 dilution.
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