anti-HMGA2 / HMGI-C antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG65035
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes HMGA2 / HMGI-C |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Dog |
| 应用 | WB |
| 特异性 | This antibody is expected to recognize both reported isoforms (NP_003474.1; NP_003475.1) and is not expected to cross-react with HMGA1. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HMGA2 / HMGI-C |
| 抗原物种 | Human |
| 抗原 | C-KAAQKKAEATGEK |
| 偶联标记 | Un-conjugated |
| 別名 | HMGIC; BABL; LIPO; HMGI-C; High mobility group AT-hook protein 2; STQTL9; High mobility group protein HMGI-C |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P52926 Human High mobility group protein HMGI-C |
|---|---|
| 背景介绍 | This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| 研究领域 | Cancer antibody; Developmental Biology antibody; Gene Regulation antibody; Metabolism antibody; Neuroscience antibody |
| 预测分子量 | 12 kDa |
| 翻译后修饰 | Regulated by cell cycle-dependent phosphorylation which alters its DNA binding affinity. Phosphorylated by NEK2 (By similarity). |
检测图片 (1)
ARG65035 anti-HMGA2 / HMGI-C antibody WB image
Western blot: Human Heart lysate (35 µg protein in RIPA buffer) stained with ARG65035 anti-HMGA2 / HMGI-C antibody at 1 µg/ml dilution.
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