anti-HPRT1 antibody [1D9]
![anti-HPRT1 antibody [1D9]](/upload/image/products/ARG57547_WB_1_210_205.jpg)
![anti-HPRT1 antibody [1D9]](/upload/image/products/ARG57547_WB_1.jpg)
Key features and details
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- 克隆:
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- 抗原物种:
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CAT.NO. : ARG57547
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [1D9] recognizes HPRT1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1D9 |
| 同位型 | IgG2b, kappa |
| 靶点名称 | HPRT1 |
| 抗原物种 | Human |
| 抗原 | Recombinant Human HPRT (aa. 1-218) purified from E. coli. |
| 偶联标记 | Un-conjugated |
| 別名 | EC 2.4.2.8; Hypoxanthine-guanine phosphoribosyltransferase; HGPRTase; HGPRT; HPRT |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P00492 Human Hypoxanthine-guanine phosphoribosyltransferase |
|---|---|
| 基因名称 | HPRT1 |
| 全名 | hypoxanthine phosphoribosyltransferase 1 |
| 背景介绍 | The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.[provided by RefSeq, Jun 2009] |
| 生物功能 | Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway. [UniProt] |
| 预测分子量 | 25 kDa |
检测图片 (1)
ARG57547 anti-HPRT antibody [1D9] WB image
Western blot: 40 µg of HeLa, MCF7, 293T and A549 cell lysates stained with ARG57547 anti-HPRT antibody [1D9] at 1:1000 dilution.
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