anti-HPRT1 antibody
CAT.NO. : ARG43898
US$ Please choose
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概述
产品描述 | Rabbit Polyclonal antibody recognizes HPRT1 |
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反应物种 | Hu, Ms, Rat |
应用 | ELISA, FACS, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | HPRT1 |
抗原物种 | Human |
抗原 | Human HPRT1 recombinant protein |
表达系统 | E.coli |
偶联标记 | Un-conjugated |
Protein Full name | Hypoxanthine-guanine phosphoribosyltransferase |
別名 | HPRT1; Hypoxanthine Phosphoribosyltransferase 1; HGPRT; HPRT; Hypoxanthine Guanine Phosphoribosyl Transferase; Hypoxanthine-Guanine Phosphoribosyltransferase; EC 2.4.2.8; HGPRTase; Hypoxanthine-Guanine Phosphoribosyltransferase 1; Testicular Tissue Protein Li 89; Lesch-Nyhan Syndrome |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
数据库连接 | Swiss-port # P00492 Human Hypoxanthine-guanine phosphoribosyltransferase Swiss-port # P27605 Rat Hypoxanthine-guanine phosphoribosyltransferase |
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基因名称 | HPRT1 |
全名 | Hypoxanthine Phosphoribosyltransferase 1 |
背景介绍 | The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout. |
生物功能 | Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway. |
细胞定位 | Cytoplasm |
预测分子量 | 25 kDa |
翻译后修饰 | Acetylation, Isopeptide bond Phosphoprotein, Ubl conjugation |
检测图片 (4)
ARG43898 anti-HPRT1 antibody WB image
Western blot: Hela and 293T stained with ARG43898 anti-HPRT1 antibody at 0.5 μg/mL dilution.
ARG43898 anti-HPRT1 antibody FACS image
Flow Cytometry: 293T cells stained with ARG43898 anti-HPRT1 antibody (blue) at 1 μg/1x10^6 cells dilution.
ARG43898 anti-HPRT1 antibody WB image
Western blot: Mouse brain stained with ARG43898 anti-HPRT1 antibody at 0.5 μg/mL dilution.
ARG43898 anti-HPRT1 antibody WB image
Western blot: Rat brain stained with ARG43898 anti-HPRT1 antibody at 0.5 μg/mL dilution.
