anti-HPV16 L1 antibody [CamVir-1]
CAT.NO. : ARG56108
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概述
产品描述 | Mouse Monoclonal antibody [CamVir-1] recognizes HPV16 L1 |
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反应物种 | HPV |
应用 | ICC/IF, IHC-P |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | CamVir-1 |
同位型 | IgG2a, kappa |
靶点名称 | HPV16 L1 |
抗原物种 | Virus |
抗原 | Human papilloma virus type 16, major capsid protein L1. |
偶联标记 | Un-conjugated |
別名 | Major capsid protein L1 |
应用说明
交叉反应性说明 | Virus (HPV-16) | ||||||
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应用建议 |
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应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in 10 mM Citrate buffer (pH 6.0) for 10-20 min, followed by cooling at RT for 20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purification with Protein G. |
缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA |
抗菌剂 | 0.05% Sodium azide |
稳定剂 | 0.1 mg/ml BSA |
浓度 | 0.2 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | L1 |
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全名 | major capsid L1 protein |
生物功能 | Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2. [UniProt] |
细胞定位 | Nuclear |
