anti-HSD11B1 antibody
Key features and details
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- 预测物种:
- 应用:
- 特异性:
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- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG63708
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes HSD11B1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Cow |
| 应用 | WB |
| 特异性 | This antibody is expected to recognise human HSD11B1 protein. Both NP_005516.1 and NP_861420.1 variants encode the same protein. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HSD11B1 |
| 抗原物种 | Human |
| 抗原 | CTSYNMDRFINK |
| 偶联标记 | Un-conjugated |
| 別名 | Corticosteroid 11-beta-dehydrogenase isozyme 1; 11-DH; Short chain dehydrogenase/reductase family 26C member 1; HSD11B; EC 1.1.1.146; 11-beta-hydroxysteroid dehydrogenase 1; HSD11L; HSD11; SDR26C1; HDL; 11-beta-HSD1; CORTRD2 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P28845 Human Corticosteroid 11-beta-dehydrogenase isozyme 1 |
|---|---|
| 背景介绍 | The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011] |
| 研究领域 | Cancer antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 32 kDa |
| 翻译后修饰 | Glycosylated. |
检测图片 (1)
ARG63708 anti-HSD11B1 antibody WB image
Western blot: Human Liver lysate (35 µg protein in RIPA buffer) stained with ARG63708 anti-HSD11B1 antibody at 0.3 µg/ml dilution.
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