anti-HSD17B11 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG66738
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HSD17B11 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HSD17B11 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide between aa. 71-120 of Human HSD17B11. |
| 偶联标记 | Un-conjugated |
| 別名 | Cutaneous T-cell lymphoma-associated antigen HD-CL-03; CTCL-associated antigen HD-CL-03; 17-beta-hydroxysteroid dehydrogenase 11; retSDR2; 17-beta-HSD XI; Short chain dehydrogenase/reductase family 16C member 2; 17-beta-HSD 11; SDR16C2; 17betaHSD11; Dehydrogenase/reductase SDR family member 8; PAN1B; 17-beta-hydroxysteroid dehydrogenase XI; 17BHSD11; RETSDR2; Estradiol 17-beta-dehydrogenase 11; 17bHSD11; 17-BETA-HSD11; DHRS8; 17-BETA-HSDXI; Retinal short-chain dehydrogenase/reductase 2; EC 1.1.1.62; 17betaHSDXI |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | 293 and Raw264.7 | ||||
| 实际分子量 | 32 ~ 34 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q8NBQ5 Human Estradiol 17-beta-dehydrogenase 11 Swiss-port # Q9EQ06 Mouse Estradiol 17-beta-dehydrogenase 11 |
|---|---|
| 基因名称 | HSD17B11 |
| 全名 | hydroxysteroid (17-beta) dehydrogenase 11 |
| 背景介绍 | Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).[supplied by OMIM, Jun 2009] |
| 生物功能 | Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 33 kDa |
检测图片 (2)
ARG66738 anti-HSD17B11 antibody WB image
Western blot: 293 cell lysate stained with ARG66738 anti-HSD17B11 antibody.
ARG66738 anti-HSD17B11 antibody WB image
Western blot: Raw264.7 cell lysate stained with ARG66738 anti-HSD17B11 antibody.
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