anti-Hsp 60 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Hsp 60
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Hsp 60
  • 抗原物种: Human
  • 抗原: Synthetic peptide around aa. 480-560 (C-terminus) of Human Hsp60.
  • Brand:
CAT.NO. : ARG65733
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Hsp 60
反应物种Hu, Ms, Rat
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Hsp 60
抗原物种Human
抗原Synthetic peptide around aa. 480-560 (C-terminus) of Human Hsp60.
偶联标记Un-conjugated
別名Heat shock protein 60; HuCHA60; 60 kDa heat shock protein, mitochondrial; GROEL; P60 lymphocyte protein; 60 kDa chaperonin; HSP-60; Mitochondrial matrix protein P1; HLD4; SPG13; HSP60; Chaperonin 60; Hsp60; CPN60; HSP65
应用说明
应用建议
应用推荐稀释比
ICC/IF1:100 - 1:500
IHC-P1:50 - 1:100
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS, 0.02% Sodium azide, 0.5% BSA and 50% Glycerol
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA, 50% Glycerol
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 15510 Mouse HSPD1

GeneID: 3329 Human HSPD1

GeneID: 63868 Rat HSPD1

基因名称HSPD1
全名heat shock 60kDa protein 1 (chaperonin)
背景介绍This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]
生物功能Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. [UniProt]
研究领域Controls and Markers antibody; Signaling Transduction antibody; Mitochondrial Marker antibody
预测分子量61 kDa
检测图片 (4)
  • ARG65733 anti-Hsp 60 antibody WB image

    Western blot: LOVO, NIH-3T3, and Rat muscle cell lysates (left to right) stained with ARG65733 anti-Hsp 60 antibody.

  • ARG65733 anti-Hsp 60 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human lung carcinoma tissue stained wih ARG65733 anti-Hsp 60 antibody at 1:50 dilution.

  • ARG65733 anti-Hsp 60 antibody ICC/IF image

    Immunocytochemistry: HepG2 cells stained with ARG65733 anti-Hsp 60 antibody at 1:100 dilution.

  • ARG65733 anti-Hsp 60 antibody WB image

    Western blot: COLO205 cells stained with ARG65733 anti-Hsp 60 antibody.

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