anti-ICT1 antibody [1E9]

CAT.NO. : ARG57122

US＄ Please choose

Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [1E9] recognizes ICT1
反应物种	Hu
应用	FACS, WB
宿主	Mouse
克隆	Monoclonal
克隆号	1E9
同位型	IgG1, kappa
靶点名称	ICT1
抗原物种	Human
抗原	Recombinant fragment around aa. 30-206 of Human ICT1
偶联标记	Un-conjugated
別名	39S ribosomal protein L58, mitochondrial; DS-1; MRP-L58; DS1; Peptidyl-tRNA hydrolase ICT1, mitochondrial; EC 3.1.1.29; Digestion substraction 1; Immature colon carcinoma transcript 1 protein

应用说明

应用建议

应用	推荐稀释比
FACS	Assay-dependent
WB	1:1000

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 3396 Human ICT1 Swiss-port # Q14197 Human Peptidyl-tRNA hydrolase ICT1, mitochondrial
基因名称	ICT1
全名	immature colon carcinoma transcript 1
背景介绍	The protein encoded by this gene is a peptidyl-tRNA hydrolase and a vital component of the large mitochondrial ribosome. The encoded protein serves as a ribosome release factor for this ribosome, which translates mitochondrial genes. This protein may be responsible for degrading prematurely-terminated polypeptides and for reusing stalled ribosomes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]
生物功能	Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. [UniProt]
预测分子量	24 kDa

检测图片 (3)

ARG57122 anti-ICT1 antibody [1E9] FACS image
Flow Cytometry: A549 cell line stained with ARG57122 anti-ICT1 antibody [1E9] at 2-5 µg for 1x10^6 cells. Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate.
ARG57122 anti-ICT1 antibody [1E9] WB image
Western blot: 40 µg of A549 and HeLa cell lysates stained with ARG57122 anti-ICT1 antibody [1E9] at 1:1000.
ARG57122 anti-ICT1 antibody [1E9] WB image
Western blot: 5 µg of 1) 293T, and 2) ICT Transfected 293T cell lysate stained with ARG57122 anti-ICT1 antibody [1E9] at 1:1000.

New Products