anti-IDO1 / INDO antibody [10.1]
![anti-IDO1 / INDO antibody [10.1]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG23317
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [10.1] recognizes IDO1 / INDO |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-Fr, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 10.1 |
| 同位型 | IgG3 |
| 靶点名称 | IDO1 / INDO |
| 抗原物种 | Human |
| 抗原 | GST-fused synthetic peptide around aa. 78-184 of Human IDO1. |
| 偶联标记 | Un-conjugated |
| 別名 | IDO-1; Indoleamine 2,3-dioxygenase 1; IDO; Indoleamine-pyrrole 2,3-dioxygenase; INDO; EC 1.13.11.52 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | WB: This product recognizes a 45 kDa band in IFN-gamma treated human cell lines. This antibody recognizes a slightly lower molecular weight band in Mouse IDO compared to its human counterpart. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified |
| 缓冲液 | PBS |
| 抗菌剂 | 0.1% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IDO1 |
| 全名 | indoleamine 2,3-dioxygenase 1 |
| 背景介绍 | This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011] |
| 生物功能 | Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen. [UniProt] |
| 预测分子量 | 45 kDa |
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