anti-IDO1 / INDO antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes IDO1 / INDO
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Dog
  • 应用: WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: IDO1 / INDO
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG63890
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes IDO1 / INDO
反应物种Hu
预测物种Ms, Rat, Dog
应用WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称IDO1 / INDO
抗原物种Human
抗原Synthetic peptide around the internal region of Human INDO / IDO. (NP_002155.1, CVLANWKKKDPNK)
偶联标记Un-conjugated
別名IDO-1; Indoleamine 2,3-dioxygenase 1; IDO; Indoleamine-pyrrole 2,3-dioxygenase; INDO; EC 1.13.11.52
应用说明
应用建议
应用推荐稀释比
WB0.5 - 1.5 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量~ 50 kDa
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 3620 Human IDO1

Swiss-port # P14902 Human Indoleamine 2,3-dioxygenase 1

背景介绍This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
产品亮点Related products:
INDO antibodies; Anti-Goat IgG secondary antibodies;
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研究领域Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody
预测分子量45 kDa
检测图片 (3)
  • ARG63890 anti-IDO1 / INDO antibody IHC-P image

    Immunohistochemistry: Human Placenta stained with ARG63890 anti-IDO1 / INDO antibody at 6 µg/ml dilution.

  • ARG63890 anti-IDO1 / INDO antibody WB image

    Western blot: Human lymph node stained with ARG63890 anti-IDO1 / INDO antibody at 0.5 µg/ml dilution.

  • ARG63890 anti-IDO1 / INDO antibody WB image

    Western blot: Human Placenta stained with ARG63890 anti-IDO1 / INDO antibody at 0.5 µg/ml dilution.

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