anti-IFIT2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG54736
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IFIT2 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IFIT2 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 307-335 (Center) of Human IFIT2 (NP_001538.4). |
| 偶联标记 | Un-conjugated |
| 別名 | IFI-54K; IFIT-2; IFI-54; ISG54; ISG-54 K; cig42; Interferon-induced protein with tetratricopeptide repeats 2; Interferon-induced 54 kDa protein; P54; GARG-39; G10P2; IFI54; ISG-54K |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | 293 |
属性
| 纯化 | Protein A purified |
|---|---|
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P09913 Human Interferon-induced protein with tetratricopeptide repeats 2 |
|---|---|
| 基因名称 | IFIT2 |
| 全名 | interferon-induced protein with tetratricopeptide repeats 2 |
| 生物功能 | IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis. [UniProt] |
| 细胞定位 | Cytoplasm. Endoplasmic reticulum |
| 研究领域 | Immune System antibody; Signaling Transduction antibody |
| 预测分子量 | 55 kDa |
检测图片 (1)
ARG54736 anti-IFIT2 antibody WB image
Western blot: 35 µg of 293 cell lysate stained with ARG54736 anti-IFIT2 antibody.
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