anti-IGF2BP1 / IMP1 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes IGF2BP1 / IMP1.
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Cow, Dog
  • 应用: IHC-P, WB
  • 特异性: This antibody is expected to recognize both reported isoforms (NP_006537.3; NP_001153895.1).
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: IGF2BP1 / IMP1
  • Brand:
CAT.NO. : ARG65273
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes IGF2BP1 / IMP1.
反应物种Hu
预测物种Ms, Rat, Cow, Dog
应用IHC-P, WB
特异性This antibody is expected to recognize both reported isoforms (NP_006537.3; NP_001153895.1).
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称IGF2BP1 / IMP1
抗原物种Human
抗原C-EKVFAEHKISYSGQ
偶联标记Un-conjugated
別名VICKZ1; CRDBP; IMP1; IMP-1; ZBP-1; ZBP1; CRD-BP; VICKZ family member 1; IGF2 mRNA-binding protein 1; IGF-II mRNA-binding protein 1; Zipcode-binding protein 1; Coding region determinant-binding protein; Insulin-like growth factor 2 mRNA-binding protein 1
应用说明
应用建议
应用推荐稀释比
IHC-P3 - 5 µg/ml
WB0.3 - 1 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 10642 Human IGF2BP1

Swiss-port # Q9NZI8 Human Insulin-like growth factor 2 mRNA-binding protein 1

背景介绍This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
研究领域Gene Regulation antibody
预测分子量63 kDa
翻译后修饰Phosphorylated. Phosphorylation may impair association with ACTB mRNA and hence abolishes translational repression (By similarity).
检测图片 (2)
  • ARG65273 anti-IGF2BP1 / IMP1 antibody WB image

    Western Blot: K562 lysate (35 µg protein in RIPA buffer) stained with ARG65273 anti-IGF2BP1 / IMP1 antibody at 0.3 µg/ml dilution.

  • ARG65273 anti-IGF2BP1 / IMP1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human breast tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG65273 anti-IGF2BP1 / IMP1 antibody at 3.75 µg/ml dilution followed by AP-staining.

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