anti-IGF2BP3 antibody [SQab30341]

CAT.NO. : ARG67068

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Size:

100 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Recombinant Rabbit Monoclonal antibody [SQab30341] recognizes IGF2BP3
反应物种	Hu
应用	IHC-P
宿主	Rabbit
克隆	Monoclonal
克隆号	SQab30341
同位型	IgG
靶点名称	IGF2BP3
抗原物种	Human
抗原	Recombinant protein fragment of IGF2BP3
偶联标记	Un-conjugated
Protein Full name	IGF2BP3
別名	IGF2BP3; Insulin Like Growth Factor 2 MRNA Binding Protein 3; IMP 3; IMP3; CT98; Insulin-Like Growth Factor 2 MRNA-Binding Protein 3; IGF-II MRNA-Binding Protein 3; IGF2 MRNA-Binding Protein 3; Cancer/Testis Antigen 98; VICKZ Family Member 3; VICKZ3; KOC1; KH Domain Containing Protein Overexpressed In Cancer; KH Domain-Containing Protein Overexpressed In Cancer; Insulin-Like Growth Factor 2 MRNA Binding Protein 3; IGF II MRNA Binding Protein 3; HKOC; KOC

应用说明

应用建议

应用	推荐稀释比
IHC-P	1:100-1:200

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
抗菌剂	0.01% Sodium azide
稳定剂	40% Glycerol and 0.05% BSA
存放说明	-20°C
注意事项	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.

生物信息

数据库连接	GeneID: 10643 Human IGF2BP3 Swiss-port # O00425 Human Insulin-like growth factor 2 mRNA-binding protein 3
基因名称	IGF2BP3
全名	Insulin Like Growth Factor 2 MRNA Binding Protein 3
背景介绍	The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]
生物功能	RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability . [UniProt]
细胞定位	Cytoplasm, Nucleusd. [UniProt]
预测分子量	64 kDa
翻译后修饰	Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt]

检测图片 (1)

ARG67068 anti-IGF2BP3 antibody [SQab30341] IHC-P image
Immunohistochemistry: Human pancreatic cancer tissue stained with ARG67068anti-IGF2BP3 antibody [SQab30341] at 1:100 dilution.

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