anti-IGFBP3 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes IGFBP3
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Dog
  • 应用: WB
  • 特异性: This antibody is expected to recognise both reported isoforms (NP_001013416.1 and NP_000589.2).
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: IGFBP3
  • Brand:
CAT.NO. : ARG64343
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes IGFBP3
反应物种Hu
预测物种Ms, Rat, Dog
应用WB
特异性This antibody is expected to recognise both reported isoforms (NP_001013416.1 and NP_000589.2).
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称IGFBP3
抗原物种Human
抗原C-RYKVDYESQSTDTQN
偶联标记Un-conjugated
別名IBP-3; IBP3; Insulin-like growth factor-binding protein 3; IGFBP-3; IGF-binding protein 3; BP-53
应用说明
应用建议
应用推荐稀释比
WB0.02 - 0.06 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 3486 Human IGFBP3

Swiss-port # P17936 Human Insulin-like growth factor-binding protein 3

背景介绍This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
研究领域Cell Biology and Cellular Response antibody; Cell Death antibody; Metabolism antibody; Signaling Transduction antibody
预测分子量32 kDa
翻译后修饰Phosphorylated by FAM20C in the extracellular medium.
检测图片 (1)
  • ARG64343 anti-IGFBP3 antibody WB image

    Western Blot: Human Breast cancer lysate (35 µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. stained with ARG64343 anti-IGFBP3 antibody at 0.02 µg/ml dilution.

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