anti-IL10 antibody

Key features and details

  • 产品描述: Rat Monoclonal antibody recognizes IL10
  • 反应物种: Ms, Rat
  • 应用: Neut, WB, sELISA
  • 宿主: Rat
  • 克隆: Monoclonal
  • 同位型: IgG2a
  • 靶点名称: IL10
  • 抗原物种: Mouse
  • 抗原: E.coli derived recombinant mouse IL-10
  • Brand:
CAT.NO. : ARG65674
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Product Details
概述
产品描述Rat Monoclonal antibody recognizes IL10
反应物种Ms, Rat
应用Neut, WB, sELISA
宿主Rat
克隆Monoclonal
同位型IgG2a
靶点名称IL10
抗原物种Mouse
抗原E.coli derived recombinant mouse IL-10
偶联标记Un-conjugated
別名IL10A; GVHDS; TGIF; IL-10; Cytokine synthesis inhibitory factor; CSIF; Interleukin-10
应用说明
应用建议
应用推荐稀释比
Neut3 - 5 µg/ml (To yield ND50 of the biological activity of Murine IL-10 at a concentration of 0.5 ng/ml)
WB1 - 2 µg/ml
sELISA4 - 8 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS (pH 7.2)
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 16153 Mouse IL10

GeneID: 25325 Rat IL10

Swiss-port # P18893 Mouse Interleukin-10

Swiss-port # P29456 Rat Interleukin-10

基因名称Il10
全名interleukin 10
背景介绍This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, Sep 2015]
生物功能Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. [UniProt]
研究领域Cancer antibody; Immune System antibody
预测分子量21 kDa
检测图片 (2)
  • ARG65674 anti-IL10 antibody WB image

    Western blot: 250 - 0.24 ng (left to right) of recombinant Mouse IL-10 stained with ARG65674 anti-IL10 antibody.

  • ARG65674 anti-IL10 antibody standard curve image

    ARG65674 anti-IL10 antibody results of a typical standard run with optical density reading at 405 - 650 nm.

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