anti-IL10 antibody [CC320] (Biotin)

产品描述: Biotin-conjugated Mouse Monoclonal antibody [CC320] recognizes IL10This antibody recognizes bovine IL-10.Mouse anti Bovine Interleukin-10 antibody, clone CC320 has been shown to neutralize the activity of bovine IL-10 as measured by the inhibition of the inhibitory activity of IL-10 on IFN gamma synthesis (Buza et al. 2004).
反应物种: Bov, Goat, Hrs, Sheep
应用: ELISA
宿主: Mouse
克隆: Monoclonal
克隆号: CC320
同位型: IgG1
靶点名称: IL10
抗原物种: Bovine

CAT.NO. : ARG22452

US＄ Please choose

Size:

100 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Biotin-conjugated Mouse Monoclonal antibody [CC320] recognizes IL10 This antibody recognizes bovine IL-10.Mouse anti Bovine Interleukin-10 antibody, clone CC320 has been shown to neutralize the activity of bovine IL-10 as measured by the inhibition of the inhibitory activity of IL-10 on IFN gamma synthesis (Buza et al. 2004).
反应物种	Bov, Goat, Hrs, Sheep
应用	ELISA
宿主	Mouse
克隆	Monoclonal
克隆号	CC320
同位型	IgG1
靶点名称	IL10
抗原物种	Bovine
抗原	Plasmid cDNA encoding bovine IL-10.
偶联标记	Biotin
別名	IL10A; GVHDS; TGIF; IL-10; Cytokine synthesis inhibitory factor; CSIF; Interleukin-10

应用说明

应用建议

应用	推荐稀释比
ELISA	5 - 10 µg/ml

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS and 0.09% Sodium azide
抗菌剂	0.09% Sodium azide
浓度	1 mg/ml
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 281246 Bovine IL10 Swiss-port # P43480 Bovine Interleukin-10
基因名称	IL10
全名	interleukin 10
背景介绍	The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
生物功能	Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. [UniProt]
预测分子量	21 kDa

New Products