anti-IL10 antibody [JES5-16E3] (Biotin)

Key features and details

  • 产品描述: Biotin-conjugated Rat Monoclonal antibody [JES5-16E3 ] recognizes IL10
  • 反应物种: Ms
  • 应用: ELISA, ELISPOT, FACS, ICC/IF, IHC-Fr, Neut
  • 特异性: Mouse IL-10.
  • 宿主: Rat
  • 克隆: Monoclonal
  • 克隆号: JES5-16E3
  • 同位型: IgG2b, kappa
  • 靶点名称: IL10
  • Brand:
CAT.NO. : ARG21480
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Product Details
概述
产品描述Biotin-conjugated Rat Monoclonal antibody [JES5-16E3 ] recognizes IL10
反应物种Ms
应用ELISA, ELISPOT, FACS, ICC/IF, IHC-Fr, Neut
特异性Mouse IL-10.
宿主Rat
克隆Monoclonal
克隆号JES5-16E3
同位型IgG2b, kappa
靶点名称IL10
抗原物种Mouse
抗原E. coli-expressed mouse IL-10
偶联标记Biotin
別名IL10A; GVHDS; TGIF; IL-10; Cytokine synthesis inhibitory factor; CSIF; Interleukin-10
应用说明
应用建议
应用推荐稀释比
ELISA1:1000 - 1:2000
ELISPOTAssay-dependent
FACSAssay-dependent
ICC/IFAssay-dependent
IHC-FrAssay-dependent
NeutAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液PBS and 0.1% Sodium azide.
抗菌剂0.1% Sodium azide
浓度0.5 mg/ml
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 16153 Mouse IL10

Swiss-port # P18893 Mouse Interleukin-10

基因名称IL10
全名interleukin 10
背景介绍The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
生物功能Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. [UniProt]
预测分子量21 kDa
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