anti-IL12RB1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG65240
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes IL12RB1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 特异性 | This antibody is expected to recognize isoform 1 (NP_005526.1) only. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IL12RB1 |
| 抗原物种 | Human |
| 抗原 | C-HVSVKNHSLDSVS |
| 偶联标记 | Un-conjugated |
| 別名 | Interleukin-12 receptor subunit beta-1; IL-12R-beta-1; IL12RB; IL-12R-BETA1; IL-12 receptor beta component; IL-12RB1; IL-12 receptor subunit beta-1; IMD30; CD212; IL-12R subunit beta-1; CD antigen CD212 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P42701 Human Interleukin-12 receptor subunit beta-1 |
|---|---|
| 背景介绍 | The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| 研究领域 | Immune System antibody |
| 预测分子量 | 73 kDa |
检测图片 (1)
ARG65240 anti-IL12RB1 antibody WB image
Western Blot: Peripharal Blood Lymphocytes lysate (35 µg protein in RIPA buffer) stained with ARG65240 anti-IL12RB1 antibody at 0.3 µg/ml dilution.
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