anti-IL15 antibody [B-E29] (low endotoxin)
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Key features and details
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CAT.NO. : ARG23355
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Product Details
概述
| 产品描述 | Azide free and low endotoxin Mouse Monoclonal antibody [B-E29] recognizes IL15 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS, FuncSt |
| 特异性 | This antibody recognizes both natural and recombinant human IL-15. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | B-E29 |
| 同位型 | IgG1 |
| 靶点名称 | IL15 |
| 抗原物种 | Human |
| 抗原 | Recombinant human IL-15 |
| 偶联标记 | Un-conjugated |
| 別名 | IL-15; Interleukin-15 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | Sterile-filtered through 0.22 µm and treated to remove endotoxins. |
| 缓冲液 | PBS |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL15 |
| 全名 | interleukin 15 |
| 背景介绍 | The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011] |
| 生物功能 | Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha. [UniProt] |
| 预测分子量 | 18 kDa |
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