anti-IL17 / IL17A antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
Product Details
| 产品描述 | Rabbit Polyclonal antibody recognizes IL17 / IL17A |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IL17 / IL17A |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human IL17A (NP_002181.1). |
| 偶联标记 | Un-conjugated |
| 別名 | IL-17A; Interleukin-17A; IL-17; CTLA8; IL17; CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8 |
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Rat liver and Mouse liver. |
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | |
|---|---|
| 基因名称 | IL17A |
| 全名 | interleukin 17A |
| 背景介绍 | The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008] |
| 生物功能 | Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. [UniProt] |
| 产品亮点 | Related products: IL17 antibodies; IL17 ELISA Kits; IL17 recombinant proteins; Anti-Rabbit IgG secondary antibodies; Related news: HMGB1, a biomarker and therapeutic target in COVID-19 |
| 研究领域 | Cancer antibody; Immune System antibody |
| 预测分子量 | 18 kDa |
| 翻译后修饰 | Found both in glycosylated and nonglycosylated forms. |
ARG55256 anti-IL17 / IL17A antibody WB image
Western blot: 25 µg of Rat liver and Mouse liver lysates stained with ARG55256 anti-IL17 / IL17A antibody at 1:1000 dilution.
ARG55256 anti-IL17 / IL17A antibody WB image
Western blot: Extracts of normal (lane 1), retinopathy of prematurity (lane 2) and VEGF/rho transgenic mice (lane 3) stained with ARG55256 anti-IL17 / IL17A antibody.
Expected signal was at 18 kDa, and the 36 kDa signal in figure might be dimer form of IL17 protein.
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