anti-IL1A antibody

Key features and details

  • 产品描述: Mouse Monoclonal antibody recognizes IL1A
  • 反应物种: Hu
  • 应用: ELISA, IHC-P, IP
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 同位型: IgG2b
  • 靶点名称: IL1A
  • 抗原物种: Human
  • 偶联标记: Un-conjugated
  • Brand:
CAT.NO. : ARG44679
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Product Details
概述
产品描述Mouse Monoclonal antibody recognizes IL1A
反应物种Hu
应用ELISA, IHC-P, IP
宿主Mouse
克隆Monoclonal
同位型IgG2b
靶点名称IL1A
抗原物种Human
偶联标记Un-conjugated
別名IL-1 alpha; Interleukin-1 alpha; IL1; IL1F1; Hematopoietin-1; IL1-ALPHA; IL-1A
应用说明
应用建议
应用推荐稀释比
ELISA5 µg/mL
IHC-P5-10 µg/mL
IP10 µg/mL
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Protein A purification
缓冲液PBS with 0.09% sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 3552 Human IL1A

Swiss-port # P01583 Human Interleukin-1 alpha

基因名称Il1a
全名interleukin 1 alpha
背景介绍The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
生物功能Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. [UniProt]
检测图片 (2)
  • ARG44679 anti-IL1A antibody IHC-P image

    Immunohistochemistry: Human Liver stained with ARG44679 anti-IL1A antibody at 10 µg/mL dilution.

  • ARG44679 anti-IL1A antibody IP image

    Immunoprecipitation: THP-1(LPS treated) lysate immunoprecipitated with 2.5 µg of ARG44679 anti-IL1A antibody.

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