anti-IL21 antibody (Biotin)

Key features and details

  • 产品描述: Biotin-conjugated Rabbit Polyclonal antibody recognizes IL21
  • 反应物种: Hu
  • 应用: ELISA, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: IL21
  • 抗原物种: Human
  • 抗原: E.coli derived Recombinant Human IL-21.(MQDRHMIRMR QLIDIVDQLK NYVNDLVPEF LPAPEDVETN CEWSAFSCFQ KAQLKSANTG NNERIINVSI KKLKRKPPST NAGRRQKHRL TCPSCDSYEK KPPKEFLERF KSLLQKMIHQ HLSSRTHGSE DS)
  • Brand:
CAT.NO. : ARG56790
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Product Details
概述
产品描述Biotin-conjugated Rabbit Polyclonal antibody recognizes IL21
反应物种Hu
应用ELISA, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称IL21
抗原物种Human
抗原E.coli derived Recombinant Human IL-21.
(MQDRHMIRMR QLIDIVDQLK NYVNDLVPEF LPAPEDVETN CEWSAFSCFQ KAQLKSANTG NNERIINVSI KKLKRKPPST NAGRRQKHRL TCPSCDSYEK KPPKEFLERF KSLLQKMIHQ HLSSRTHGSE DS)
偶联标记Biotin
別名Za11; IL-21; CVID11; Interleukin-21
应用说明
应用建议
应用推荐稀释比
ELISADirect: 0.25 - 1.0 µg/ml
Sandwich: 0.25 - 1.0 µg/ml with ARG56680 as a capture antibody
WB0.1 - 0.2 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified by affinity chromatography.
缓冲液PBS (pH 7.2)
浓度1 mg/ml
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 59067 Human IL21

Swiss-port # Q9HBE4 Human Interleukin-21

基因名称IL21
全名interleukin 21
背景介绍This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
生物功能Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. [UniProt]
预测分子量19 kDa
检测图片 (2)
  • ARG56790 anti-IL21 antibody (Biotin) standard curve image

    Direct ELISA: ARG56790 anti-IL21 antibody (Biotin) at 0.25 - 1.0 µg/ml results of a typical standard run with optical density.

  • ARG56790 anti-IL21 antibody (Biotin) standard curve image

    Sandwich ELISA: ARG56790 anti-IL21 antibody (Biotin) as a detection antibody at 0.25 - 1.0 µg/ml combined with ARG56680 anti-IL21 antibody as a capture antibody. Results of a typical standard run with optical density.

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