anti-IL5 antibody [JES1-5A10] (Biotin)
CAT.NO. : ARG21440
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概述
| 产品描述 | Biotin-conjugated Rat Monoclonal antibody [JES1-5A10 ] recognizes IL5 |
|---|---|
| 反应物种 | Hu, Bb, R. Mk |
| 应用 | ELISA, ELISPOT, FACS, Neut |
| 特异性 | Human/Rhesus/Cynomolgus/Baboon/Sooty Mangabey IL-5. |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | JES1-5A10 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | IL5 |
| 抗原物种 | Human |
| 抗原 | COS-expressed human IL-5 |
| 偶联标记 | Biotin |
| 別名 | Eosinophil differentiation factor; EDF; IL-5; TRF; T-cell replacing factor; B-cell differentiation factor I; Interleukin-5 |
应用说明
| 应用建议 |
| ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS and 0.1% Sodium azide. |
| 抗菌剂 | 0.1% Sodium azide |
| 浓度 | 0.5 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL5 |
| 全名 | interleukin 5 |
| 背景介绍 | This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013] |
| 生物功能 | Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. [UniProt] |
| 预测分子量 | 15 kDa |
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