anti-IL6 antibody [B-E8]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [B-E8] recognizes IL6Mouse anti Human Interleukin-6 antibody, clone B-E8 recognizes human interleukin-6 (IL-6), a cytokine and potent inducer of the immune acute phase response.
  • 反应物种: Hu
  • 不反应物种: Ms
  • 应用: ELISA, FuncSt, IHC-Fr
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: B-E8
  • 同位型: IgG1
  • 靶点名称: IL6
  • Brand:
CAT.NO. : ARG23312
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Product Details
概述
产品描述Mouse Monoclonal antibody [B-E8] recognizes IL6
Mouse anti Human Interleukin-6 antibody, clone B-E8 recognizes human interleukin-6 (IL-6), a cytokine and potent inducer of the immune acute phase response.
反应物种Hu
不反应物种Ms
应用ELISA, FuncSt, IHC-Fr
宿主Mouse
克隆Monoclonal
克隆号B-E8
同位型IgG1
靶点名称IL6
抗原物种Human
抗原Recombinant full-length Human IL6 expressed in E. coli.
偶联标记Un-conjugated
別名B-cell stimulatory factor 2; CDF; HSF; BSF-2; Interferon beta-2; IL-6; IFNB2; CTL differentiation factor; Interleukin-6; HGF; Hybridoma growth factor; BSF2; IFN-beta-2
应用说明
应用建议
应用推荐稀释比
ELISAAssay-dependent
FuncSt20 pg neutralizes activity of 1U of IL-6
IHC-FrAssay-dependent
应用说明Functional assay: This product contains sodium azide, removal by dialysis is recommended prior to use in functional assays.
IHC-Fr: The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. Arigo recommends the use of acetone fixation for frozen sections.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified by ion exchange chromatography.
缓冲液PBS and 0.09% Sodium azide.
抗菌剂0.09% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 3569 Human IL6

Swiss-port # P05231 Human Interleukin-6

基因名称IL6
全名interleukin 6
背景介绍This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]
生物功能Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. [UniProt]
产品亮点Related products:
IL6 antibodies; IL6 ELISA Kits; IL6 recombinant proteins; Anti-Mouse IgG secondary antibodies;
Related news:
HMGB1 in inflammation
Inflammatory Cytokines
预测分子量24 kDa
翻译后修饰N- and O-glycosylated. [UniProt]
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