anti-Influenza A Virus Hemagglutinin antibody [C102]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [C102] recognizes Influenza A Virus Hemagglutinin
  • 反应物种: Influenza A
  • 应用: ELISA, ICC/IF, IHC-Fr, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: C102
  • 同位型: IgG1
  • 靶点名称: Influenza A Virus Hemagglutinin
  • 抗原物种: Mouse
  • Brand:
CAT.NO. : ARG10313
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Product Details
概述
产品描述Mouse Monoclonal antibody [C102] recognizes Influenza A Virus Hemagglutinin
反应物种Influenza A
应用ELISA, ICC/IF, IHC-Fr, WB
宿主Mouse
克隆Monoclonal
克隆号C102
同位型IgG1
靶点名称Influenza A Virus Hemagglutinin
抗原物种Mouse
抗原Purified influenza virus type A strain H1N1 (strain: A/Kazakhstan/Seagull/470)
偶联标记Un-conjugated
应用说明
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Protein G affinity purified.
缓冲液PBS (pH 7.4) and 0.1% Sodium azide
抗菌剂0.1% Sodium azide
浓度1.0-2.0 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称HA
全名hemagglutinin
生物功能Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore (By similarity). [UniProt]
研究领域Microbiology and Infectious Disease antibody
预测分子量64 kDa
检测图片 (1)
  • ARG10313 anti-Influenza A Virus Hemagglutinin antibody [C102] ELISA image

    ELISA: Specific activity of MAb C102 in ELISA with purified virus antigen A (H1N1). MAb C102 was obtained by use of avian influenza virus strain A (H1N1) as an immunogen and it is directed against relatively conservative H1 epitope. MAb cross reactivity pattern shows that it does not react with H3 and other haemagglutinins but interacts with H1 from human and avian influenza viruses, having indirect ELISA titers not less than 1:128 K.

参考文献

克隆号文献

Localization and force analysis at the single virus particle level using atomic force microscopy.

Liu CH et al.
Biochem Biophys Res Commun.,  (2012)

publication_link

 

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A method to generate recombinant Salmonella typhi Ty21a strains expressing multiple heterologous genes using an improved recombineering strategy.

WB / 

Yu B et al.
Appl Microbiol Biotechnol.,  (2011)

publication_link

 

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Electrical detection of single viruses.

Patolsky F et al.
Proc Natl Acad Sci U S A.,  (2004)

publication_link

 

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