anti-IQGAP2 antibody
CAT.NO. : ARG44684
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概述
产品描述 | Mouse Monoclonal antibody recognizes IQGAP2 |
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反应物种 | Hu |
应用 | IP, WB |
宿主 | Mouse |
克隆 | Monoclonal |
同位型 | IgG1 |
靶点名称 | IQGAP2 |
抗原物种 | Human |
偶联标记 | Un-conjugated |
別名 | Ras GTPase-activating-like protein IQGAP2 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein A purification |
缓冲液 | PBS with 0.09% sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q13576 Human Ras GTPase-activating-like protein IQGAP2 |
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基因名称 | IQGAP2 |
全名 | IQ motif containing GTPase activating protein 2 |
背景介绍 | This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. [provided by RefSeq, Jul 2008] |
生物功能 | Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin. [UniProt] |
预测分子量 | 181 kDa |
翻译后修饰 | N-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER. |
