anti-IRAK2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes IRAK2
  • 反应物种: Hu, Ms
  • 应用: ICC/IF, WB
  • 特异性: At least four isoforms of IRAK2 are known to exist; this antibody will detect all four isoforms. The antibody has no cross-reactivity with IRAK1.
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: IRAK2
  • 抗原物种: Mouse
  • Brand:
CAT.NO. : ARG40407
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes IRAK2
反应物种Hu, Ms
应用ICC/IF, WB
特异性At least four isoforms of IRAK2 are known to exist; this antibody will detect all four isoforms. The antibody has no cross-reactivity with IRAK1.
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称IRAK2
抗原物种Mouse
抗原A peptide (17 amino acids) within the last 50 amino acids of Mouse IRAK2.
偶联标记Un-conjugated
別名IRAK-2; Interleukin-1 receptor-associated kinase-like 2
应用说明
应用建议
应用推荐稀释比
ICC/IF10 - 20 µg/ml
WB0.5 - 2 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Raw264.7
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS and 0.02% Sodium azide.
抗菌剂0.02% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 108960 Mouse IRAK2

GeneID: 3656 Human IRAK2

Swiss-port # O43187 Human Interleukin-1 receptor-associated kinase-like 2

Swiss-port # Q8CFA1 Mouse Interleukin-1 receptor-associated kinase-like 2

基因名称IRAK2
全名interleukin-1 receptor-associated kinase 2
背景介绍IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. [provided by RefSeq, Jul 2008]
生物功能Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. [UniProt]
预测分子量69 kDa
检测图片 (4)
  • ARG40407 anti-IRAK2 antibody ICC/IF image

    Immunofluorescence: A20 cells stained with ARG40407 anti-IRAK2 antibody at 10 µg/ml dilution.

  • ARG40407 anti-IRAK2 antibody WB image

    Western blot: Raw264.7 whole cell lysate stained with ARG40407 anti-IRAK2 antibody at 0.5, 1 and 2 µg/ml dilution.

  • ARG40407 anti-IRAK2 antibody ICC/IF image

    Immunofluorescence: HeLa cells stained with ARG40407 anti-IRAK2 antibody (red) at 20 µg/ml dilution. DAPI (blue) for nuclear staining.

  • ARG40407 anti-IRAK2 antibody ICC image

    Immunocytochemistry: A20 cells stained with ARG40407 anti-IRAK2 antibody at 1 µg/ml dilution.

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