anti-IRAK2 antibody
CAT.NO. : ARG40407
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概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IRAK2 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 特异性 | At least four isoforms of IRAK2 are known to exist; this antibody will detect all four isoforms. The antibody has no cross-reactivity with IRAK1. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IRAK2 |
| 抗原物种 | Mouse |
| 抗原 | A peptide (17 amino acids) within the last 50 amino acids of Mouse IRAK2. |
| 偶联标记 | Un-conjugated |
| 別名 | IRAK-2; Interleukin-1 receptor-associated kinase-like 2 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Raw264.7 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # O43187 Human Interleukin-1 receptor-associated kinase-like 2 Swiss-port # Q8CFA1 Mouse Interleukin-1 receptor-associated kinase-like 2 |
|---|---|
| 基因名称 | IRAK2 |
| 全名 | interleukin-1 receptor-associated kinase 2 |
| 背景介绍 | IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. [provided by RefSeq, Jul 2008] |
| 生物功能 | Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. [UniProt] |
| 预测分子量 | 69 kDa |
检测图片 (4)
ARG40407 anti-IRAK2 antibody ICC/IF image
Immunofluorescence: A20 cells stained with ARG40407 anti-IRAK2 antibody at 10 µg/ml dilution.
ARG40407 anti-IRAK2 antibody WB image
Western blot: Raw264.7 whole cell lysate stained with ARG40407 anti-IRAK2 antibody at 0.5, 1 and 2 µg/ml dilution.
ARG40407 anti-IRAK2 antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG40407 anti-IRAK2 antibody (red) at 20 µg/ml dilution. DAPI (blue) for nuclear staining.
ARG40407 anti-IRAK2 antibody ICC image
Immunocytochemistry: A20 cells stained with ARG40407 anti-IRAK2 antibody at 1 µg/ml dilution.
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