anti-IRAK3 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
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- 克隆:
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- 靶点名称:
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- 抗原:
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Brand:
CAT.NO. : ARG64632
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes IRAK3 |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IRAK3 |
| 抗原物种 | Mouse |
| 抗原 | C-GHSYGSKPMEKR |
| 偶联标记 | Un-conjugated |
| 別名 | ASRT5; IRAK-3; IRAKM; IRAK-M; IL-1 receptor-associated kinase M; Interleukin-1 receptor-associated kinase 3; EC 2.7.11.1 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q8K4B2 Mouse Interleukin-1 receptor-associated kinase 3 |
|---|---|
| 基因名称 | Irak3 |
| 全名 | interleukin-1 receptor-associated kinase 3 |
| 背景介绍 | This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| 生物功能 | Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. [UniProt] |
| 研究领域 | Immune System antibody; Signaling Transduction antibody |
| 预测分子量 | 68 kDa |
检测图片 (2)
ARG64632 anti-IRAK3 antibody WB image
Western blot: 35 µg of Mouse bone marrow lysates (Left: Wild type. Right: KO) stained with ARG64632 anti-IRAK3 antibody at 0.5 µg/ml dilution, overnight at 4°C.
ARG64632 anti-IRAK3 antibody WB image
Western blot: 35 μg of Rat liver lysate (in RIPA buffer) stained with ARG64632 anti-IRAK3 antibody at 0.05 μg/ml dilution and incubated at RT for 1 hour.
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