anti-IRF6 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes IRF6
  • 反应物种: Hu
  • 应用: IHC-P, WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: IRF6
  • 抗原物种: Human
  • 抗原: C-TPSMQLPPALPPQ
  • Brand:
CAT.NO. : ARG63443
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes IRF6
反应物种Hu
应用IHC-P, WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称IRF6
抗原物种Human
抗原C-TPSMQLPPALPPQ
偶联标记Un-conjugated
別名Interferon regulatory factor 6; PPS1; LPS; VWS; PPS; VWS1; OFC6; PIT; IRF-6
应用说明
应用建议
应用推荐稀释比
IHC-P2 - 5 µg/ml
WB0.2 - 0.6 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 3664 Human IRF6

Swiss-port # O14896 Human Interferon regulatory factor 6

背景介绍This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011]
研究领域Developmental Biology antibody; Gene Regulation antibody; Immune System antibody
预测分子量53 kDa
翻译后修饰Phosphorylated. Phosphorylation status depends on the cell cycle and is a signal for ubiquitination and proteasome-mediated degradation.
检测图片 (4)
  • ARG63443 anti-IRF6 antibody WB image

    Western Blot: Human Ovary lysate (RIPA buffer, 35 µg total protein per lane) stained with ARG63443 anti-IRF6 antibody at 0.2 µg/ml dilution.

  • ARG63443 anti-IRF6 antibody WB image

    Western Blot: 1). Mock transfection; 2) IRF6 (RC201579) expressing plasmid transfected HEK293 cell lysate standed with ARG63443 anti-IRF6 antibody

  • ARG63443 anti-IRF6 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human prostate tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63443 anti-IRF6 antibody at 5 µg/ml dilution followed by AP-staining.

  • ARG63443 anti-IRF6 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Kidney. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63443 anti-IRF6 antibody at 2.5 µg/ml dilution followed by AP-staining.

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