anti-ITGB1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes ITGB1
  • 反应物种: Hu, Rat
  • 应用: ELISA, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: ITGB1
  • 抗原物种: Human
  • 抗原: Human ITGB1 recombinant protein
  • Brand:
CAT.NO. : ARG43959
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes ITGB1
反应物种Hu, Rat
应用ELISA, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称ITGB1
抗原物种Human
抗原Human ITGB1 recombinant protein
表达系统E.coli
偶联标记Un-conjugated
Protein Full nameIntegrin beta-1
別名ITGB1; Integrin Subunit Beta 1; GPIIA; MSK12; CD29; FNRB; MDF2; Integrin, Beta 1 (Fibronectin Receptor, Beta Polypeptide, Antigen CD29 Includes MDF2, MSK12); Glycoprotein IIa; Integrin Beta-1; Very Late Activation Protein, Beta Polypeptide; Fibronectin Receptor Subunit Beta; Integrin VLA-4 Beta Subunit; VLA-4 Subunit Beta; Integrin Beta 1; CD29 Antigen; VLA-BETA; VLAB
应用说明
应用建议
应用推荐稀释比
ELISA0.1-0.5 µg/ml
WB0.25-0.5 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose.
稳定剂4% Trehalose
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
生物信息
数据库连接

GeneID: 24511 Rat ITGB1

GeneID: 3688 Human ITGB1

Swiss-port # P05556 Human Integrin beta-1

Swiss-port # P49134 Rat Integrin beta-1

基因名称ITGB1
全名Integrin Subunit Beta 1
背景介绍Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
生物功能Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion.
细胞定位Cell junction, Cell membrane, Cell projection, Endosome, Membrane
预测分子量88 kDa
翻译后修饰Acetylation, Disulfide bond, Glycoprotein, Isopeptide bond, Phosphoprotein, Ubl conjugation
检测图片 (1)
  • ARG43959 anti-ITGB1 antibody FACS image

    Flow Cytometry: HeLa and A431 cells stained with ARG43959anti-ITGB1 antibody (blue) at 1 μg/1x10^6 cells dilution.

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