anti-KCNN2 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes KCNN2
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Cow, Dog
  • 应用: IHC-P, WB
  • 特异性: This antibody is expected to recognize both isoforms (NP_067627.2; NP_740721.1).
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: KCNN2
  • Brand:
CAT.NO. : ARG65085
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes KCNN2
反应物种Hu
预测物种Ms, Rat, Cow, Dog
应用IHC-P, WB
特异性This antibody is expected to recognize both isoforms (NP_067627.2; NP_740721.1).
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称KCNN2
抗原物种Human
抗原C-ESYDKHVTYNAER
偶联标记Un-conjugated
別名KCa2.2; SK2; hSK2; SKCA2; Small conductance calcium-activated potassium channel protein 2; SKCa2; SKCa 2
应用说明
应用建议
应用推荐稀释比
IHC-P3 - 5 µg/ml
WB0.3 - 1 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 3781 Human KCNN2

Swiss-port # Q9H2S1 Human Small conductance calcium-activated potassium channel protein 2

背景介绍Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
研究领域Neuroscience antibody
预测分子量64 kDa
检测图片 (3)
  • ARG65085 anti-KCNN2 antibody WB image

    Western Blot: Human Liver lysate (35 µg protein in RIPA buffer) stained with ARG65085 anti-KCNN2 antibody at 0.3 µg/ml dilution.

  • ARG65085 anti-KCNN2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human kidney tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG65085 anti-KCNN2 antibody at 3.75 µg/ml dilution followed by AP-staining.

  • ARG65085 anti-KCNN2 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Thyroid Gland. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG65085 anti-KCNN2 antibody at 3.8 µg/ml dilution followed by AP-staining.

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