anti-Kindlin1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG44325
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Kindlin1 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Bov, Dog, NHuPrm, Xenopus |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Kindlin1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide |
| 偶联标记 | Un-conjugated |
| 別名 | FERMT1; FERM Domain Containing Kindlin 1; KIND1; URP1; UNC112A; Fermitin Family Homolog 1; Unc-112-Related Protein 1; Fermitin Family Member 1; Kindlin Syndrome Protein; Kindlin-1; Kindlerin; FLJ20116; C20orf42; Fermitin Family Homolog 1 (Drosophila); Chromosome 20 Open Reading Frame 42; UNC112 Related Protein 1; Kinderlin; Kindlin 1; C20ORF42; DTGCU2 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified |
| 缓冲液 | PBS with 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FERMT1 |
| 全名 | FERM Domain Containing Kindlin 1 |
| 背景介绍 | This gene encodes a member of the fermitin family, and contains a FERM domain and a pleckstrin homology domain. The encoded protein is involved in integrin signaling and linkage of the actin cytoskeleton to the extracellular matrix. Mutations in this gene have been linked to Kindler syndrome. |
| 生物功能 | Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression. |
| 细胞定位 | Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane |
| 预测分子量 | 77 kDa |
| 翻译后修饰 | Phosphoprotein |
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