anti-KIST antibody
CAT.NO. : ARG54858
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概述
产品描述 | Rabbit Polyclonal antibody recognizes KIST |
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反应物种 | Hu, Ms |
预测物种 | Rat |
应用 | IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | KIST |
抗原物种 | Human |
抗原 | KLH-conjugated synthetic peptide corresponding to aa. 1-30 (N-terminus) of Human KIST. |
偶联标记 | Un-conjugated |
別名 | PAM COOH-terminal interactor protein 2; KIS; Kinase interacting with stathmin; KIST; Serine/threonine-protein kinase Kist; P-CIP2; EC 2.7.11.1; U2AF homology motif kinase 1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | A549 |
属性
形式 | Liquid |
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纯化 | Purification with Protein G. |
缓冲液 | PBS and 0.09% (W/V) Sodium azide |
抗菌剂 | 0.09% (W/V) Sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P97343 Mouse Serine/threonine-protein kinase Kist Swiss-port # Q8TAS1 Human Serine/threonine-protein kinase Kist |
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基因名称 | UHMK1 |
全名 | U2AF homology motif (UHM) kinase 1 |
背景介绍 | The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
生物功能 | Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity). [UniProt] |
细胞定位 | Nucleus. |
研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Signaling Transduction antibody |
预测分子量 | 47 kDa |
