anti-KMT3C / SMYD2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG43462
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KMT3C / SMYD2. |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | KMT3C / SMYD2 |
| 抗原物种 | Human |
| 抗原 | Purified recombinant protein corresponding to human KMT3C / SMYD2. |
| 偶联标记 | Un-conjugated |
| Protein Full name | N-lysine methyltransferase SMYD2 |
| 別名 | KMT3C; HSKM-B; ZMYND14 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SMYD2 |
| 全名 | SET and MYND domain containing 2 |
| 背景介绍 | SET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006 [PubMed 16805913]).[supplied by OMIM, Nov 2008] |
| 生物功能 | Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'. [UniProt] |
检测图片 (2)
ARG43462 anti-KMT3C / SMYD2 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG43462 anti-KMT3C / SMYD2 antibody.
ARG43462 anti-KMT3C / SMYD2 antibody WB image
Western blot: HepG2 stained with ARG43462 anti-KMT3C / SMYD2 antibody at 1:2000 dilution.
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