anti-KPNA6 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes KPNA6
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Cow, Dog, Pig
  • 应用: IHC-P, WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: KPNA6
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG64586
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes KPNA6
反应物种Hu
预测物种Ms, Rat, Cow, Dog, Pig
应用IHC-P, WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称KPNA6
抗原物种Human
抗原C-STTGESVITREMVE
偶联标记Un-conjugated
別名KPNA7; Importin subunit alpha-7; IPOA7; Karyopherin subunit alpha-6
应用说明
应用建议
应用推荐稀释比
IHC-P3 - 6 µg/ml
WB0.1 - 0.3 µg/ml
应用说明IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 23633 Human KPNA6

Swiss-port # O60684 Human Importin subunit alpha-7

背景介绍Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008]
研究领域Signaling Transduction antibody
预测分子量60 kDa
检测图片 (2)
  • ARG64586 anti-KPNA6 antibody WB image

    Western Blot: Human Muscle lysate (35 µg protein in RIPA buffer) stained with ARG64586 anti-KPNA6 antibody at 0.1 µg/ml dilution.

  • ARG64586 anti-KPNA6 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Adrenal Gland. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG64586 anti-KPNA6 antibody at 3.8 µg/ml dilution followed by AP-staining.

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