anti-Kv3.1 phospho (Ser503) antibody
Key features and details
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- 抗原:
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Brand:
CAT.NO. : ARG52399
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Kv3.1 phospho (Ser503) |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | IHC, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Kv3.1 |
| 抗原物种 | Rat |
| 抗原 | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser503 conjugated to KLH |
| 偶联标记 | Un-conjugated |
| 別名 | Potassium voltage-gated channel subfamily C member 1; EPM7; NGK2; KV3.1; KV4; Voltage-gated potassium channel subunit Kv4; Voltage-gated potassium channel subunit Kv3.1 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | Specific for the ~100k Kv3.1 voltage-gated potassium channel protein phosphorylated at Ser503. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P15388 Mouse Potassium voltage-gated channel subfamily C member 1 Swiss-port # P25122 Rat Potassium voltage-gated channel subfamily C member 1 |
|---|---|
| 基因名称 | KCNC1 |
| 全名 | potassium channel, voltage gated Shaw-related subfamily C, member 1 |
| 背景介绍 | Voltage-gated K+ channels are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types (Maletic-Savatic et al., 1995; Pongs, 1999; Blaine and Ribera, 1998; Burger and Ribera, 1996). The Kv3.1 potassium channel is expressed at high levels in neurons that characteristically fire rapid trains of action potentials (Gan et al., 1999). |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 58 kDa |
| 翻译后修饰 | N-glycosylated; contains sialylated glycans. |
检测图片 (1)
ARG52399 anti-Kv3.1 phospho (Ser503) antibody ICC/IF image
Immunofluorescence: medial nucleus of the trapezoid body (MNTB) cells stained with ARG52399 anti-Kv3.1 phospho (Ser503) antibody.
The left panel shows control cells.
The right panel shows cells that have been exposed to the protein kinase C activator PMA.
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