anti-Kv4.3 antibody
Key features and details
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- 反应物种:
- 应用:
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- 宿主:
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- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG20564
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Kv4.3 |
|---|---|
| 反应物种 | Ms |
| 应用 | WB |
| 特异性 | This antibody is reactive to the 74 kDa mouse Kv4.3 in mouse brain tissue extract on Western blot. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Kv4.3 |
| 抗原物种 | Mouse |
| 抗原 | KLH-conjugated synthetic peptide around aa. 55-64 of Mouse voltage-gated potassium channel Kv4.3. (RTTLERYPDT) |
| 偶联标记 | Un-conjugated |
| 別名 | Kv4.3; KV4.3; Potassium voltage-gated channel subfamily D member 3; Kncd3; AW045978; KCND3S; BRGDA9; SCA19; KSHIVB; SCA22; Voltage-gated potassium channel subunit Kv4.3; KCND3L |
应用说明
| 应用建议 |
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属性
| 形式 | Powder |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | Lyophilized in 0.01M PBS (pH 7.4) |
| 复溶 | 100 μl of double distilled water is recommended to adjust the final concentration to 1.0 mg/ml. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q9Z0V1 Mouse Potassium voltage-gated channel subfamily D member 3 |
|---|---|
| 基因名称 | Kcnd3 |
| 全名 | potassium voltage-gated channel, Shal-related family, member 3 |
| 背景介绍 | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Neuroscience antibody |
| 预测分子量 | 73 kDa |
| 翻译后修饰 | Regulated through phosphorylation at Ser-569 by CaMK2D. |
检测图片 (1)
ARG20564 anti-Kv4.3 antibody WB image
Western blot: extracts from Mouse brain stained with ARG20564 anti-Kv4.3 antibody.
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