anti-Laminin antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes LamininThis antibody recognizes both A (400kD) and B (220kD) chains of laminin.
  • 反应物种: Hu, Ms, Bird, Chk, Dog, Duck, Pig, Rb
  • 应用: ELISA, ICC/IF, IHC-Fr, IHC-P
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Laminin
  • 抗原物种: Mouse
  • 抗原: Purified laminin from Engelbreth-Holm-Swarm (EHS).
  • Brand:
CAT.NO. : ARG22704
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Laminin
This antibody recognizes both A (400kD) and B (220kD) chains of laminin.
反应物种Hu, Ms, Bird, Chk, Dog, Duck, Pig, Rb
应用ELISA, ICC/IF, IHC-Fr, IHC-P
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Laminin
抗原物种Mouse
抗原Purified laminin from Engelbreth-Holm-Swarm (EHS).
偶联标记Un-conjugated
別名LAMA1: S-LAM-alpha; LAMA; Laminin-1 subunit alpha; PTBHS; Laminin-3 subunit alpha; S-LAM alpha; S-laminin subunit alpha; Laminin A chain; Laminin subunit alpha-1

LAMA2: Laminin-12 subunit alpha; Laminin-2 subunit alpha; Laminin-4 subunit alpha; Merosin heavy chain; Laminin M chain; LAMM; Laminin subunit alpha-2

LAMB1: Laminin-1 subunit beta; CLM; Laminin-8 subunit beta; Laminin-10 subunit beta; Laminin B1 chain; Laminin-12 subunit beta; LIS5; Laminin-2 subunit beta; Laminin-6 subunit beta; Laminin subunit beta-1

LAMB2: Laminin-3 subunit beta; S-laminin subunit beta; Laminin B1s chain; S-LAM beta; Laminin-4 subunit beta; LAMS; NPHS5; Laminin-14 subunit beta; Laminin-15 subunit beta; Laminin-9 subunit beta; Laminin-11 subunit beta; Laminin-7 subunit beta; Laminin subunit beta-2
应用说明
应用建议
应用推荐稀释比
ELISA> 1:1000
ICC/IFAssay-dependent
IHC-Fr1:200 - 1:1000
IHC-PAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液Serum and 0.09% Sodium azide.
抗菌剂0.09% Sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称LAMA1; LAMA2; LAMB1; LAMB2
全名laminin, alpha 1; laminin, alpha 2; laminin, beta 1; laminin, beta 2 (laminin S)
背景介绍LAMA1: This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014]
生物功能LAMA1: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. [UniProt]
细胞定位LAMA1, LAMA2 and LAMB1: Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component. [UniProt]

LAMB2: Secreted, extracellular space, extracellular matrix, basement membrane. Note=S-laminin is concentrated in the synaptic cleft of the neuromuscular junction. [UniProt]
翻译后修饰LAMA1: Tyrosine phosphorylated by PKDCC/VLK.
检测图片 (1)
  • ARG22704 anti-Laminin antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human kidney stained with ARG22704 anti-Laminin antibody.

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