anti-LD78 beta antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG66079
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes LD78 beta |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | LD78 beta |
| 抗原物种 | Human |
| 抗原 | E. coli derived recombinant Human LD78 beta. (APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA) |
| 偶联标记 | Un-conjugated |
| 別名 | C-C motif chemokine 3-like 1; Small-inducible cytokine A3-like 1; D17S1718; SCYA3L1; 5-70; 464.2; Tonsillar lymphocyte LD78 beta protein; LD78BETA; PAT 464.2; LD78-beta; G0/G1 switch regulatory protein 19-2; 1-70; 3-70; SCYA3L; G0S19-2; LD78 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CCL3L3 |
|---|---|
| 全名 | chemokine (C-C motif) ligand 3-like 3 |
| 背景介绍 | This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility.[provided by RefSeq, Apr 2014] |
| 生物功能 | Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5. [UniProt] |
| 预测分子量 | 10 kDa |
| 翻译后修饰 | The N-terminal processed forms LD78-beta(3-70) and LD78-beta(5-70) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. The cleavage to yield LD78-beta(3-70) is probably achieved by DPP4. |
检测图片 (3)
ARG66079 anti-LD78 beta antibody WB image
Western blot: 250 - 0.24 ng of Human LD78β stained with ARG66079 anti-LD78 beta antibody, under non-reducing conditions.
ARG66079 anti-LD78 beta antibody standard curve image
Sandwich ELISA: ARG66079 anti-LD78 beta antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG66080 anti-LD78 beta antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
ARG66079 anti-LD78 beta antibody WB image
Western blot: 250 - 0.24 ng of Human LD78β stained with ARG66079 anti-LD78 beta antibody, under reducing conditions.
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