anti-LITAF antibody [5C10]

CAT.NO. : ARG56987

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [5C10] recognizes LITAF
反应物种	Hu
应用	WB
宿主	Mouse
克隆	Monoclonal
克隆号	5C10
同位型	IgG2b, kappa
靶点名称	LITAF
抗原物种	Human
抗原	Recombinant fragment around aa. 1-161 of Human LITAF.
偶联标记	Un-conjugated
別名	SIMPLE; TP53I7; Small integral membrane protein of lysosome/late endosome; Lipopolysaccharide-induced tumor necrosis factor-alpha factor; PIG7; LPS-induced TNF-alpha factor; p53-induced gene 7 protein

应用说明

应用建议

应用	推荐稀释比
WB	1:2000 - 1:3000

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 9516 Human LITAF Swiss-port # Q99732 Human Lipopolysaccharide-induced tumor necrosis factor-alpha factor
基因名称	LITAF
全名	lipopolysaccharide-induced TNF factor
背景介绍	Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2014]
生物功能	Probable role in regulating transcription of specific genes. May regulate through NFKB1 the expression of the CCL2/MCP-1 chemokine. May play a role in tumor necrosis factor alpha (TNF-alpha) gene expression. [UniProt]
预测分子量	17 kDa
翻译后修饰	Phosphorylated on tyrosine residues in response to EGF.

检测图片 (1)

ARG56987 anti-LITAF antibody [5C10] WB image
Western blot: 40 µg of HeLa and HepG2 cell lysates stained with ARG56987 anti-LITAF antibody [5C10] at 1:1000 dilution.

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