anti-LRRK2 antibody [S231B-34] (HRP)

CAT.NO. : ARG24130

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Size:

50 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	HRP-conjugated Mouse Polyclonal antibody[S231B-34] recognizes LRRK2
反应物种	Hu, Rat
应用	ICC/IF, IHC-P, WB
宿主	Mouse
克隆	Monoclonal
克隆号	S231B-34
同位型	IgG2a
靶点名称	LRRK2
抗原物种	Human
抗原	Fusion protein a.a 841-960 of human LRRK2
偶联标记	HRP
別名	PARK8; RIPK7; ROCO2; AURA17; DARDARIN; Leucine-rich repeat serine/threonine-protein kinase 2; Parkinson Disease (Autosomal Dominant) 8; Augmented In Rheumatoid Arthritis 17

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS (pH 7.4), 50% Glycerol and 0.09% Sodium azide
抗菌剂	0.09% Sodium azide
稳定剂	50% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 120892 Human LRRK2 Swiss-port # Q5S007 Human Leucine-rich repeat serine/threonine-protein kinase 2
基因名称	LRRK2
全名	leucine rich repeat kinase 2
背景介绍	This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008]
生物功能	LRRK2 (Leucine Rich Repeat Kinase 2) is a Protein Coding gene. Diseases associated with LRRK2 include Parkinson Disease 8, Autosomal Dominant and Hereditary Late-Onset Parkinson Disease. Among its related pathways are Signaling by PTK6 and ncRNAs involved in Wnt signaling in hepatocellular carcinoma. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and transferase activity, transferring phosphorus-containing groups. An important paralog of this gene is BRAF. [GeneCard]
细胞定位	Cell projection; Cytoplasmic vesicle; Endoplasmic reticulum; Endosome; Golgi apparatus; Lysosome; Membrane; Mitochondrion; Mitochondrion outer membrane; Synapse
产品亮点	Related products: anti-LRRK2 antibody [S231B-34]
预测分子量	286 kDa
翻译后修饰	Phosphoprotein

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