anti-LTB antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes LTB
  • 反应物种: Ms, Rat
  • 应用: FACS, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: LTB
  • 抗原物种: Mouse
  • 抗原: Mouse Ltb recombinant protein (aa. sequence: R68-G306).
  • Brand:
CAT.NO. : ARG44423
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes LTB
反应物种Ms, Rat
应用FACS, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称LTB
抗原物种Mouse
抗原Mouse Ltb recombinant protein (aa. sequence: R68-G306).
偶联标记Un-conjugated
別名LTB; Lymphotoxin Beta; TNFSF3; TNFC; P33; Tumor Necrosis Factor Ligand Superfamily Member 3; TNF Superfamily Member 3;Necrosis Factor C; Lymphotoxin-Beta; LT-Beta; TNF-C
应用说明
应用建议
应用推荐稀释比
FACS1-3 µg/1x10^6 cells
WB0.25-0.5 µg/ml
应用说明The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose.
抗菌剂0.05% Sodium azide
稳定剂4% Trehalose
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
生物信息
数据库连接

GeneID: 16994 Mouse LTB

Swiss-port # P41155 Mouse Lymphotoxin-beta

基因名称LTB
全名Lymphotoxin Beta
背景介绍Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
生物功能Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional.
细胞定位Membrane
预测分子量25 kDa
翻译后修饰Glycoprotein
检测图片 (2)
  • ARG44423 anti-LTB antibody WB image

    Western blot: PC-12 stained with ARG44423 anti-LTB antibody at 0.5 μg/mL dilution.

  • ARG44423 anti-LTB antibody FACS image

    Flow Cytometry: RAW264.7 stained with ARG44423 anti-LTB antibody at 1 μg/10^6 cells dilution.

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