anti-LYVE1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes LYVE1
  • 反应物种: Ms, Rat
  • 应用: FACS, ICC/IF, IHC-Fr, IHC-P
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: LYVE1
  • 抗原物种: Mouse
  • 抗原: Recombinant Mouse soluble LYVE1.
  • Brand:
CAT.NO. : ARG66602
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes LYVE1
反应物种Ms, Rat
应用FACS, ICC/IF, IHC-Fr, IHC-P
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称LYVE1
抗原物种Mouse
抗原Recombinant Mouse soluble LYVE1.
偶联标记Un-conjugated
別名Lymphatic vessel endothelial hyaluronic acid receptor 1; Hyaluronic acid receptor; LYVE-1; XLKD1; HAR; Extracellular link domain-containing protein 1; CRSBP-1; Cell surface retention sequence-binding protein 1
应用说明
应用建议
应用推荐稀释比
FACSAssay-dependent
ICC/IF1:50-1:500
IHC-Fr1:50-1:500
IHC-P1:50-1:800
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液PBS
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 114332 Mouse LYVE1

Swiss-port # Q8BHC0 Mouse Lymphatic vessel endothelial hyaluronic acid receptor 1

基因名称LYVE1
全名lymphatic vessel endothelial hyaluronan receptor 1
背景介绍This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008]
生物功能Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. [UniProt]
细胞定位Membrane; Single-pass type I membrane protein. Note=Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface. [UniProt]
预测分子量35 kDa
翻译后修饰O-glycosylated. [UniProt]
检测图片 (4)
  • ARG66602 anti-LYVE1 antibody IHC-Fr image

    Immunohistochemistry: Cryo sections of Mouse colon carcinoma tissue stained with ARG66602 anti-LYVE1 antibody (red) and anti-Human CD31 (green). CD31; LYVE1; Merged (left to right).

  • ARG66602 anti-LYVE1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse intestine tissue stained with ARG66602 anti-LYVE1 antibody.

  • ARG66602 anti-LYVE1 antibody IHC image

    Immunohistochemistry: Rat cardiac lymphatic microvessels, stained with anti-Rat Podoplanin at 1:400 dilution (left panel) and ARG66602 anti-LYVE1 antibody at 1:1000 dilution (right panel).

  • ARG66602 anti-LYVE1 antibody IHC-Fr image

    Immunohistochemistry: Frozen section of Mouse prostate stained with ARG66602 anti-LYVE1 antibody.

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