anti-M-CSF antibody (Biotin)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
Product Details
| 产品描述 | Biotin-conjugated Rabbit Polyclonal antibody recognizes M-CSF |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | M-CSF |
| 抗原物种 | Human |
| 抗原 | E. coli derived recombinant Human M-CSF. (MEEVSEYCSH MIGSGHLQSL QRLIDSQMET SCQITFEFVD QEQLKDPVCY LKKAFLLVQD IMEDTMRFRD NTPNAIAIVQ LQELSLRLKS CFTKDYEEHD KACVRTFYET PLQLLEKVKN VFNETKNLLD KDWNIFSKNC NNSFAECSSQ GHERQSEGS) |
| 偶联标记 | Biotin |
| 別名 | Macrophage colony-stimulating factor 1; CSF-1; Lanimostim; M-CSF; MCSF |
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
| 形式 | Liquid |
|---|---|
| 纯化 | Purified by affinity chromatography. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | Swiss-port # P09603 Human Macrophage colony-stimulating factor 1 |
|---|---|
| 基因名称 | CSF1 |
| 全名 | colony stimulating factor 1 (macrophage) |
| 背景介绍 | The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] |
| 生物功能 | Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. [UniProt] |
| 预测分子量 | 60 kDa |
| 翻译后修饰 | N- and O-glycosylated. Glycosylation and proteolytic cleavage yield different soluble forms. One high molecular weight soluble form is a proteoglycan containing chondroitin sulfate. O-glycosylated with core 1 or possibly core 8 glycans. Isoform 1 is N- and O-glycosylated. Isoform 3 is only N-glycosylated. |
ARG66009 anti-M-CSF antibody (Biotin) WB image
Western blot: 250 - 0.24 ng of Human M-CSF stained with ARG66009 anti-M-CSF antibody (Biotin), under non-reducing conditions.
ARG66009 anti-M-CSF antibody (Biotin) standard curve image
Direct ELISA: ARG66009 anti-M-CSF antibody (Biotin) at 0.25 - 1.0 µg/ml results of a typical standard run with optical density reading at 405 - 650 nm.
ARG66009 anti-M-CSF antibody (Biotin) WB image
Western blot: 250 - 0.24 ng of Human M-CSF stained with ARG66009 anti-M-CSF antibody (Biotin), under reducing conditions.
ARG66009 anti-M-CSF antibody (Biotin) standard curve image
Sandwich ELISA: ARG66009 anti-M-CSF antibody (Biotin) as a detection antibody at 0.25 - 1.0 µg/ml combined with ARG66008 anti-M-CSF antibody as a capture antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
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