anti-MAEL antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG44135
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Product Details
概述
| 产品描述 | Rabbit Polyclonal recognizes MAEL |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MAEL |
| 抗原物种 | Human |
| 抗原 | Human MAEL recombinant protein (Position: E73-Q347). |
| 偶联标记 | Un-conjugated |
| 別名 | MAEL; Maelstrom Spermatogenic Transposon Silencer; SPATA35; CT128; Spermatogenesis Associated 35; Cancer/Testis Antigen 128; Protein Maelstrom Homolog; FLJ14904; Testicular Tissue Protein Li 116; Maelstrom Homolog (Drosophila); Maelstrom Homolog |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MAEL |
| 全名 | Maelstrom Spermatogenic Transposon Silencer |
| 背景介绍 | Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in gamete generation; negative regulation of macromolecule metabolic process; and piRNA metabolic process. Predicted to act upstream of or within several processes, including homologous chromosome pairing at meiosis; intrinsic apoptotic signaling pathway in response to DNA damage; and negative regulation of macromolecule metabolic process. Predicted to be located in piP-body. Predicted to be active in P granule and nucleus. |
| 生物功能 | Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage. |
| 细胞定位 | Cytoplasm, Nucleus |
| 预测分子量 | 49 kDa |
检测图片 (2)
ARG44135 anti-MAEL antibody WB image
Western blot: K562 and U251 stained with ARG44135 anti-MAEL antibody at 0.5 μg/ml dilution.
ARG44135 anti-MAEL antibody FACS image
Flow Cytometry: U251 stained with ARG44135 anti-MAEL antibody at 1 µg/10^6 cells dilution.
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