anti-MAP2 antibody (N-term)

Key features and details

  • 产品描述: Mouse Monoclonal antibody recognizes MAP2
  • 反应物种: Hu, Ms
  • 应用: ICC/IF, IP, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 同位型: IgG2b
  • 靶点名称: MAP2
  • 抗原物种: Human
  • 抗原: Purified recombinant human MAP2 (N-terminus) protein fragments expressed in E.coli
  • Brand:
CAT.NO. : ARG54031
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Product Details
概述
产品描述Mouse Monoclonal antibody recognizes MAP2
反应物种Hu, Ms
应用ICC/IF, IP, WB
宿主Mouse
克隆Monoclonal
同位型IgG2b
靶点名称MAP2
抗原物种Human
抗原Purified recombinant human MAP2 (N-terminus) protein fragments expressed in E.coli
偶联标记Un-conjugated
別名MAP2A; Microtubule-associated protein 2; MAP2C; MAP2B; MAP-2
应用说明
应用建议
应用推荐稀释比
ICC/IF1:150
IPAssay-dependent
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量300 kDa
属性
形式Liquid
纯化Affinity purified
缓冲液0.1M Tris-Glycine (pH 7.4), 150mM NaCl, 0.2%Sodium azide, 0.1%BSA and 50%Glycerol
抗菌剂0.2%Sodium azide
稳定剂0.1%BSA, 50%Glycerol
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 17756 Mouse MAP2

GeneID: 4133 Human MAP2

Swiss-port # P11137 Human Microtubule-associated protein 2

Swiss-port # P20357 Mouse Microtubule-associated protein 2

基因名称MAP2
全名microtubule-associated protein 2
背景介绍The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization.They also seem to have a stiffening effect on microtubules.
生物功能The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. [UniProt]
细胞定位Cytoplasm, cytoskeleton
产品亮点Related products:
MAP2 antibodies; MAP2 Duos / Panels; Anti-Mouse IgG secondary antibodies;
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预测分子量200 kDa
翻译后修饰Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Isoform 2 is probably phosphorylated by PKA at Ser-323, Ser-354 and Ser-386 and by FYN at Tyr-67. The interaction with KNDC1 enhances MAP2 threonine phosphorylation (By similarity).
检测图片 (3)
  • ARG54031 anti-MAP2 antibody (N-term) ICC/IF image

    Immunofluorescence: HeLa cells fixed with 4% Paraformaldehyde and stained with ARG54031 anti-MAP2 antibody (N-term) at 1:100 dilution.

  • ARG54031 anti-MAP2 antibody (N-term) WB image

    Western blot: Mouse brain lysate stained with ARG54031 anti-MAP2 antibody (N-term) at 1:1000 dilution.

  • ARG54031 anti-MAP2 antibody (N-term) IP image

    Immunoprecipitation: HeLa cell lysates were immunoprecipitated and stained with ARG54031 anti-MAP2 antibody (N-term).

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