anti-MART1 / Melan A antibody [M2-7C10]
![anti-MART1 / Melan A antibody [M2-7C10]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
Key features and details
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- 应用:
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Product Details
| 产品描述 | Mouse Monoclonal antibody [M2-7C10] recognizes MART1 / Melan A |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS, ICC/IF, IHC-Fr, IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | M2-7C10 |
| 同位型 | IgG2b, kappa |
| 靶点名称 | MART1 / Melan A |
| 抗原 | Recombinant hMART-1 protein |
| 偶联标记 | Un-conjugated |
| 別名 | MART-1; MART1; Protein Melan-A; Antigen SK29-AA; Antigen LB39-AA; Melanoma antigen recognized by T-cells 1 |
| 应用说明 | WB: 0.5-1ug/ml ELISA: 1-5ug/ml for coating FACS: 0.5-1ug/million cells ICC/IF: 1-2ug/ml IHC-F: 0.5-1ug/ml IHC-P: 0.5-1ug/ml IP: 1-2ug/500ug protein lysate * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 形式 | Liquid |
|---|---|
| 纯化 | Protein G purified |
| 缓冲液 | PBS (pH 7.4), 1% BSA and 0.05% Sodium azide |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 1% BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | Swiss-port # Q16655 Human Melanoma antigen recognized by T-cells 1 |
|---|---|
| 基因名称 | MLANA |
| 全名 | melan-A |
| 生物功能 | Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. [UniProt] |
| 细胞定位 | Cytoplasm |
| 研究领域 | Cancer antibody; Controls and Markers antibody |
| 预测分子量 | 13 kDa |
| 翻译后修饰 | Acylated. |
克隆号文献
Hypoxia contributes to melanoma heterogeneity by triggering HIF1α-dependent phenotype switching.
Vaccination with antigen-transfected, NKT cell ligand-loaded, human cells elicits robust in situ immune responses by dendritic cells.
WB / Human
A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting.
WB /
The metastatic microenvironment: brain-residing melanoma metastasis and dormant micrometastasis.
The ocular albinism type 1 (OA1) GPCR is ubiquitinated and its traffic requires endosomal sorting complex responsible for transport (ESCRT) function.
ICC/IF / Human
Intraglomerular crescentic metastases of malignant melanoma.
IHC / Human
Dendritic cell vaccine with mRNA targeted to the proteasome by polyubiquitination.
WB / Primates
Cyclobutane pyrimidine dimer formation and p53 production in human skin after repeated UV irradiation.
ICC/IF / Human
Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics.
FACS / Human
MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes.
IP / Human
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