anti-MCCC2 antibody
| 产品描述 | Rabbit Polyclonal antibody recognizes MCCC2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MCCC2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human MCCC2 |
| 偶联标记 | Un-conjugated |
| Protein Full name | Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial |
| 別名 | MCCC2; Methylcrotonyl-CoA Carboxylase Subuni 2; MCCB; 3-Methylcrotonyl-CoA Carboxylase Non-Biotin-Containing Subunit; Methylcrotonoyl-CoA Carboxylase Beta Chain, Mitochondrial; 3-Methylcrotonyl-CoA:Carbon Dioxide Ligase Subunit Beta; Methylcrotonoyl-Coenzyme A Carboxylase 2 (Beta); 3-Methylcrotonyl-CoA Carboxylase 2; MCCase Subunit Beta; EC 6.4.1.4; Non-Biotin Containing Subunit Of 3-Methylcrotonyl-CoA Carboxylase; 3-Methylcrotonyl-CoA Carboxylase Non-Biotin Containing Subunit; Methylcrotonoyl-CoA Carboxylase 2 (Beta); Methylcrotonoyl-CoA Carboxylase Beta; Testicular Secretory Protein Li 29; Methylcrotonoyl-CoA Carboxylase 2; Biotin Carboxylase; MCCCbeta; MCCCβ; MCCCB |
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | |
|---|---|
| 基因名称 | MCCC2 |
| 全名 | Methylcrotonyl-Coa Carboxylase Subunit 2 |
| 背景介绍 | This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| 生物功能 | Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism. |
| 细胞定位 | Mitochondrion |
| 预测分子量 | 61 kDa |
| 翻译后修饰 | Acetylation |
ARG44227 anti-MCCC2 antibody IHC-P image
Immunohistochemistry: Human breast cancer stained with ARG44227 anti-MCCC2 antibody at 2 μg/ml dilution.
ARG44227 anti-MCCC2 antibody WB image
Western blot: HepG2 and RT4 stained with ARG44227 anti-MCCC2 antibody at 0.25 μg/mL dilution.
ARG44227 anti-MCCC2 antibody IHC-P image
Immunohistochemistry: Rat kidney stained with ARG44227 anti-MCCC2 antibody at 2 μg/ml dilution.
ARG44227 anti-MCCC2 antibody WB image
Western blot: Rat liver and Rat kidney stained with ARG44227 anti-MCCC2 antibody at 0.25 μg/mL dilution.
ARG44227 anti-MCCC2 antibody IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG44227 anti-MCCC2 antibody at 2 μg/ml dilution.
ARG44227 anti-MCCC2 antibody WB image
Western blot: Mouse liver and Mouse kidney stained with ARG44227 anti-MCCC2 antibody at 0.25 μg/mL dilution.
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