anti-Methylmalonyl-CoA mutase antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Methylmalonyl-CoA mutase
  • 反应物种: Hu, Ms
  • 应用: ICC/IF, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Methylmalonyl-CoA mutase
  • 抗原物种: Human
  • 抗原: KLH-conjugated synthetic peptide corresponding to aa. 492-526 of Human Methylmalonyl-CoA mutase.
  • Brand:
CAT.NO. : ARG59007
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Methylmalonyl-CoA mutase
反应物种Hu, Ms
应用ICC/IF, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Methylmalonyl-CoA mutase
抗原物种Human
抗原KLH-conjugated synthetic peptide corresponding to aa. 492-526 of Human Methylmalonyl-CoA mutase.
偶联标记Un-conjugated
別名Methylmalonyl-CoA isomerase; MCM; EC 5.4.99.2; Methylmalonyl-CoA mutase, mitochondrial
应用说明
应用建议
应用推荐稀释比
ICC/IF1:25
WB1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照K562
属性
形式Liquid
纯化Purification with Protein A and immunogen peptide.
缓冲液PBS and 0.09% (W/V) Sodium azide.
抗菌剂0.09% (W/V) Sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 17850 Mouse MUT

GeneID: 4594 Human MUT

Swiss-port # P16332 Mouse Methylmalonyl-CoA mutase, mitochondrial

Swiss-port # P22033 Human Methylmalonyl-CoA mutase, mitochondrial

基因名称MUT
全名methylmalonyl CoA mutase
背景介绍This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria. [provided by RefSeq, Jul 2008]
生物功能Involved in the degradation of several amino acids, odd-chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species. [UniProt]
细胞定位Mitochondrion matrix. [UniProt]
预测分子量83 kDa
检测图片 (2)
  • ARG59007 anti-Methylmalonyl-CoA mutase antibody ICC/IF image

    Immunofluorescence: 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized HeLa cells stained with ARG59007 anti-Methylmalonyl-CoA mutase antibody (green) at 1:25 dilution. Nuclear counter stain is DAPI (blue).

  • ARG59007 anti-Methylmalonyl-CoA mutase antibody WB image

    Western blot: 20 µg of K562 cell lysate stained with ARG59007 anti-Methylmalonyl-CoA mutase antibody at 1:2000 dilution.

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